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Furthermore, TMAO exacerbates VC through dose-dependent vascular smooth muscle cell calcification and activation of the NLRP3 inflammasome and NF-B signaling (Zhang et al., 2020), thereby further promoting thrombosis (Figure 6)
Common side effects include nausea, vomiting, and injection site reactions
Lancet (2017) 390:166475
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10.3390/nu12123853 48 GruneT.LietzG.PalouA.RossA
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